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Highly Enantioselective Asymmetric Isomerization of Primary Allylic Alcohols with an Iridium–N,P Complex
Author(s) -
Li JiaQi,
Peters Byron,
Andersson Pher G.
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201101524
Subject(s) - isomerization , enantioselective synthesis , iridium , allylic rearrangement , phosphine , oxazoline , enantiomer , chemistry , primary (astronomy) , combinatorial chemistry , organic chemistry , catalysis , physics , astronomy
Access to chiral aldehydes : The asymmetric isomerization of primary allylic alcohols was studied with a bicyclic phosphine‐oxazoline iridium catalyst. This method displays a broad substrate scope and leads to the desired chiral aldehydes with excellent enantioselectivities (see scheme; R 1 , R 2 =Ar or alkyl).
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