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ortho ‐Magnesiation of Boron‐Substituted Benzenes by Using (TMP) 2 Mg
Author(s) -
Kawachi Atsushi,
Nagae Saori,
Onoue Yasuhiro,
Harada Osamu,
Yamamoto Yohsuke
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201101022
Subject(s) - boron , electrophile , medicinal chemistry , carborane , atom (system on chip) , chemistry , group (periodic table) , computer science , organic chemistry , catalysis , parallel computing
Magnesiation ortho to boron : Borylbenzenes with an N ‐methyl‐1,3‐ethylenediamino group on the boron atom undergo ortho ‐magnesiation upon exposure to 2,2,6,6‐tetramethylpiperidide (TMP) 2 Mg, and the resulting ortho ‐magnesiated borylbenzenes can be trapped with electrophiles (see scheme).