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Catalytic Asymmetric Hydrolysis: Asymmetric Hydrolytic Protonation of Enol Esters Catalyzed by Phase‐Transfer Catalysts
Author(s) -
Yamamoto Eiji,
Nagai Ayano,
Hamasaki Akiyuki,
Tokunaga Makoto
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201100833
Subject(s) - catalysis , enol , hydrolysis , chemistry , protonation , stoichiometry , hydroxide , ammonium hydroxide , phase (matter) , organic chemistry , enantioselective synthesis , ammonium , base (topology) , combinatorial chemistry , ion , mathematical analysis , mathematics
Like an enzyme : Asymmetric hydrolysis of enol esters is accomplished by chiral phase‐transfer catalysts under biphasic base hydrolysis conditions. Stoichiometric reactions support the generation of a well‐organized chiral ammonium hydroxide species (Q + OH − ).
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