Ruthenium Catalysts Containing Rigid Chiral Diamines and Achiral Diphosphanes for Highly Enantioselective Hydrogenation of Aromatic Ketones | Zendy

Zhu Qiming | Zendy; Shi Dengjian | Zendy; Xia Chungu | Zendy; Huang Hanmin | Zendy

Premium

Ruthenium Catalysts Containing Rigid Chiral Diamines and Achiral Diphosphanes for Highly Enantioselective Hydrogenation of Aromatic Ketones

Author(s) -

Zhu Qiming,

Shi Dengjian,

Xia Chungu,

Huang Hanmin

Publication year - 2011

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201100820

Subject(s) - enantioselective synthesis , ruthenium , catalysis , asymmetric hydrogenation , organic chemistry , chemistry , reactivity (psychology) , noyori asymmetric hydrogenation , diamine , combinatorial chemistry , medicine , alternative medicine , pathology

One chiral element is enough : A new ruthenium catalyst containing a rigid chiral diamine (BIDN) and a commercially available inexpensive achiral phosphane (DPPF) is highly efficient for the enantioselective hydrogenation of ketones (see scheme). High reactivity (S/C up to 100 000) and excellent enantioselectivities (up to 99 % ee ) were obtained.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research