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Zinc‐Catalyzed Chemoselective Reduction of Esters to Alcohols
Author(s) -
Das Shoubhik,
Möller Konstanze,
Junge Kathrin,
Beller Matthias
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201100800
Subject(s) - silanes , zinc , chemoselectivity , catalysis , chemistry , organic chemistry , reduction (mathematics) , functional group , combinatorial chemistry , silane , mathematics , polymer , geometry
Economical alcohols! A general and chemoselective catalytic reduction of esters to alcohols using inexpensive zinc acetate and silanes has been developed. The operational simplicity and the high functional group tolerance, without the need for protecting and deprotecting steps, make this procedure particularly attractive for organic synthesis.