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A Zinc‐Sensing Glucose‐Based Naphthyl Imino Conjugate as a Detecting Agent for Inorganic and Organic Phosphates, Including DNA
Author(s) -
Mitra Atanu,
Hinge Vijaya Kumar,
Mittal Ankit,
Bhakta Snehasis,
Guionneau Philippe,
Rao Chebrolu P.
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201100734
Subject(s) - conjugate , zinc , fluorescence , nucleotide , chemistry , aqueous solution , dna , combinatorial chemistry , biochemistry , organic chemistry , gene , physics , mathematics , mathematical analysis , quantum mechanics
Sugars' sense of zinc : A glucose‐based naphthylimino conjugate ( L ) has been synthesized and structurally characterized. L has been shown to exhibit selective turn‐on fluorescence towards Zn 2+ in an aqueous alcoholic medium. The zinc complex, in turn, recognizes phosphates, nucleotides, and DNA by turn‐off fluorescence, which has been further investigated by molecular dynamics simulations.