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Electrosynthesis as a Powerful Method for the Generation of Catalytic Intermediates: Efficient Isolation of a Palladium Aryl Halide Oxidative Addition Product
Author(s) -
Zinovyeva Veronika A.,
Luo Caihong,
Fournier Sophie,
Devillers Charles H.,
Cattey Hélène,
Doucet Henri,
Hierso JeanCyrille,
Lucas Dominique
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201100629
Subject(s) - electrosynthesis , palladium , electrolysis , combinatorial chemistry , halide , aryl , chemistry , oxidative addition , catalysis , organic chemistry , electrochemistry , alkyl , electrode , electrolyte
Polyphosphane ligands of controlled conformation promote highly efficient palladium‐catalyzed cross‐coupling reactions. Electrosynthesis has been used as a new straightforward method to obtain important intermediates in the search for a better mechanistic understanding. As a proof of concept, the facile synthesis of a phenyl iodopalladium(II) complex ( 2 ) was conducted at the electrolysis scale from a readily electrogenerated unstable Pd 0 precursor (see scheme).