Luminescent Peptide Labeling Based on a Histidine‐Binding Iridium(III) Complex for Cell Penetration and Intracellular Targeting Studies | Zendy

Wang Xiaobo | Zendy; Jia Junli | Zendy; Huang Zezhu | Zendy; Zhou Ming | Zendy; Fei Hao | Zendy

Premium

Luminescent Peptide Labeling Based on a Histidine‐Binding Iridium(III) Complex for Cell Penetration and Intracellular Targeting Studies

Author(s) -

Wang Xiaobo,

Jia Junli,

Huang Zezhu,

Zhou Ming,

Fei Hao

Publication year - 2011

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201100568

Subject(s) - intracellular , histidine , peptide , cell penetrating peptide , iridium , cell , luminescence , chemistry , computational biology , biochemistry , biophysics , biology , materials science , enzyme , optoelectronics , catalysis

Lighting up the cell : Peptides that are site‐specifically labeled with a luminescent iridium(III) complex at histidine residues can penetrate cell membranes effectively, showing intracellular distribution and efficient mitochondrial targeting (see figure, CPP=cell‐penetrating peptide, MTS=mitochondria‐targeting sequences).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research