Palladium‐Catalyzed Borylation of Aryl Mesylates and Tosylates and Their Applications in One‐Pot Sequential Suzuki–Miyaura Biaryl Synthesis | Zendy

Chow Wing Kin | Zendy; So Chau Ming | Zendy; Lau Chak Po | Zendy; Kwong Fuk Yee | Zendy

Premium

Palladium‐Catalyzed Borylation of Aryl Mesylates and Tosylates and Their Applications in One‐Pot Sequential Suzuki–Miyaura Biaryl Synthesis

Author(s) -

Chow Wing Kin,

So Chau Ming,

Lau Chak Po,

Kwong Fuk Yee

Publication year - 2011

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201100361

Subject(s) - borylation , palladium , aryl , catalysis , chemistry , indole test , combinatorial chemistry , compatibility (geochemistry) , medicinal chemistry , organic chemistry , materials science , alkyl , composite material

Top of the one‐pots! The first palladium‐catalyzed borylation of aryl tosylates and mesylates is described. The reaction conditions are mild and provide excellent functional‐group compatibility (e.g., R=CN, CHO, COOMe, C(O)R, NH 2 , or NH‐indole; see scheme). Pd/MeO‐CM‐phos allows one‐pot sequential reactions in the preparation of unsymmetrical biaryls.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research