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Inside Cover: Development of Fluorescent Glucose Bioprobes and Their Application on Real‐Time and Quantitative Monitoring of Glucose Uptake in Living Cells (Chem. Eur. J. 1/2011)
Author(s) -
Lee Hyang Yeon,
Lee Jae Jeong,
Park Jongmin,
Park Seung Bum
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201090249
Subject(s) - glucose transporter , fluorescence , chemistry , glucose uptake , biochemistry , biology , microbiology and biotechnology , insulin , physics , quantum mechanics
The perturbation … … of glucose uptake in organisms is an essential barometer in various metabolic diseases. In their Full Paper on page 143 ff. S. B. Park et al. report on a novel fluorescent glucose bioprobe that can translocate into cytoplasm by glucose‐specific transport systems through the competition with D ‐glucose. Unlike reported glucose bioprobes, such as NBDGs and 2‐deoxyglucoses, this fluorescent glucose bioprobe allows the real‐time and quantitative measurement of glucose uptake in living cells.