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Ruthenium‐Catalyzed Nitro and Nitrile Compounds Coupling with Alcohols: Alternative Route for N‐Substituted Amine Synthesis
Author(s) -
Cui Xinjiang,
Zhang Yan,
Shi Feng,
Deng Youquan
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201003095
Subject(s) - nitrile , nitrobenzene , nitro , ruthenium , amine gas treating , yield (engineering) , chemistry , catalysis , combinatorial chemistry , organic chemistry , primary (astronomy) , materials science , physics , alkyl , astronomy , metallurgy
The one‐pot synthesis of N‐substituted secondary amines from nitrobenzenes and benzonitriles has been developed (see scheme). This report presents a versatile and simple method for the synthesis of N‐substituted amines in excellent yield and high efficiency from nitro and nitrile compounds with alcohols.