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Copper‐Catalyzed Enantioselective Hydrogenation of Ketones
Author(s) -
Junge Kathrin,
Wendt Bianca,
Addis Daniele,
Zhou Shaolin,
Das Shoubhik,
Fleischer Steffen,
Beller Matthias
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201002311
Subject(s) - enantioselective synthesis , copper , denticity , catalysis , chemistry , organic chemistry , noyori asymmetric hydrogenation , combinatorial chemistry , metal
Not so precious! The combination of copper acetate and chiral monodentate ligands allows the enantioselective hydrogenation of carbonyl compounds to take place in good to high yields with moderate to good enantioselectivities (see scheme).