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Synthesis of Biaryl Compounds Using Tandem Ruthenium‐Catalyzed Ring‐Closing Metathesis
Author(s) -
Yoshida Kazuhiro,
Shida Hiroaki,
Takahashi Hidetoshi,
Yanagisawa Akira
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201002074
Subject(s) - tandem , ring closing metathesis , catalysis , ruthenium , metathesis , enyne metathesis , olefin metathesis , combinatorial chemistry , salt metathesis reaction , ring (chemistry) , closing (real estate) , chemistry , materials science , organic chemistry , polymerization , composite material , polymer , political science , law
Tandem ring‐closing enyne metathesis (RCEM)/ring‐closing olefin metathesis (RCM) of tetraenynes with Grubbs second‐generation catalyst, followed by elimination, was found to be a new and efficient synthetic approach to biaryl compounds. A preliminary asymmetric version of this approach, which used homochiral Ru–alkylidene catalysts, is also presented.