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Efficient and Clean Gold‐Catalyzed One‐Pot Selective N‐Alkylation of Amines with Alcohols
Author(s) -
He Lin,
Lou XiaBing,
Ni Ji,
Liu YongMei,
Cao Yong,
He HeYong,
Fan KangNian
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201001848
Subject(s) - alkylation , catalysis , chemistry , organic chemistry , hydrogen , combinatorial chemistry
Atom‐efficient direct N‐alkylation : An environmentally clean one‐pot selective N‐alkylation of amines with an equimolar amount of alcohols via a hydrogen autotransfer pathway was achieved over a titania‐supported gold catalyst system in good to excellent yields without additive (see scheme).