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A Simple and Effective Co‐Catalyst for Ring‐Closing Enyne Metathesis Using Grubbs I type Catalysts: A Practical Alternative to “Mori’s Conditions”
Author(s) -
LloydJones Guy C.,
Robinson Alan J.,
Lefort Laurent,
de Vries Johannes G.
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201001510
Subject(s) - enyne metathesis , ruthenium , enyne , alkene , metathesis , catalysis , chemistry , ethylene , grubbs' catalyst , combinatorial chemistry , organic chemistry , polymerization , polymer
“Catch‐and‐release” : Simple alk‐1‐enes are effective at liberating buta‐1,3‐dienes from vinyl alkylidene ruthenium complexes, as well as undergoing alkene–alkylidene exchange with enyne substrates to regenerate the alk‐1‐ene. This ability to “catch‐and‐release” ruthenium alkylidenes allows alk‐1‐enes higher than ethylene (“Mori's conditions”) to be used as a co‐catalysts in terminal enyne metathesis with the Grubbs generation I complex (L=PCy 3 ).