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Synergic Transformation of an Ethylenediamine to a Lithium 1,3‐Diaza‐2‐zincacyclopentene via an Alkyllithium/Bis(alkyl)zinc Mixture
Author(s) -
Campbell Ross,
GarcíaÁlvarez Pablo,
Kennedy Alan R.,
Mulvey Robert E.
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201001314
Subject(s) - chemistry , tetramethylethylenediamine , zincate , amide , zinc , alkali metal , lithium (medication) , alkyl , ethylenediamine , metal , medicinal chemistry , lithium amide , reagent , inorganic chemistry , electrophile , organic chemistry , catalysis , medicine , enantioselective synthesis , endocrinology
Deadly duo : Four bonds in total, two NH and two CH bonds, have been cleaved from a neutral secondary diamine through the cooperative effects of a lithium alkyl–zinc bisalkyl coalition aided by N , N , N′ , N′ ‐tetramethylethylenediamine (TMEDA) to generate a dianionic diazaethene (see scheme).