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Palladium‐Catalyzed Sonogashira Coupling of Aryl Mesylates and Tosylates
Author(s) -
Choy Pui Ying,
Chow Wing Kin,
So Chau Ming,
Lau Chak Po,
Kwong Fuk Yee
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201001269
Subject(s) - sonogashira coupling , aryl , palladium , catalysis , coupling (piping) , combinatorial chemistry , chemistry , medicinal chemistry , organic chemistry , materials science , metallurgy , alkyl
Up to speed : The first general and mild protocol for the Sonogashira coupling of aryl mesylates is presented (see scheme). The coupling intermediate also provides facile access to 2‐substituted isoquinolines.