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Selectivity in Metal‐Catalyzed CarbonCarbon Bond Cleavage of Alkylidenecyclopropanes
Author(s) -
Masarwa Ahmad,
Marek Ilan
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201001246
Subject(s) - stereocenter , reactivity (psychology) , methylene , catalysis , rationalization (economics) , carbon fibers , selectivity , metal , chemistry , bond cleavage , combinatorial chemistry , organic chemistry , materials science , enantioselective synthesis , political science , medicine , alternative medicine , pathology , composite number , law , composite material
When more complex system leads to simpler reactivity profile; the ring‐opening of strained three‐membered rings such as methylene‐ and alkylidenecyclopropanes generally lead to several products. If one starts with more functionalized carbon skeletons, selective reactions are now observed and rationalization as well as synthetic applications are described in this concept article. This methodology could be used to the preparation of challenging structural motifs possessing quaternary carbon stereocenters in acyclic systems.