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Remarkably Effective Phosphanes Simply with a PPh 2 Moiety: Application to Pd‐Catalysed Cross‐Coupling Reactions for Tetra‐ ortho ‐substituted Biaryl Syntheses
Author(s) -
So Chau Ming,
Chow Wing Kin,
Choy Pui Ying,
Lau Chak Po,
Kwong Fuk Yee
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201000723
Subject(s) - moiety , tetra , aryl , chemistry , combinatorial chemistry , coupling (piping) , coupling reaction , palladium , catalysis , stereochemistry , medicinal chemistry , organic chemistry , materials science , alkyl , metallurgy
Expanding the horizons of ArPPh 2 : New applications of triarylphosphane ligands are presented. The Pd– L1 and Pd– L2 complexes offer exceptionally high activity in Suzuki–Miyaura cross‐couplings of aryl chlorides. The extremely congested synthesis of tetra‐ ortho ‐substituted biaryl compounds is achieved for the first time by simply using triarylphosphane ligands.