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A “Clickable” Hybrid Nanocluster of Cubic Symmetry
Author(s) -
Heyl Dirk,
Rikowski Eckhard,
Hoffmann Rudolf C.,
Schneider Jörg J.,
Fessner WolfDieter
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201000488
Subject(s) - silsesquioxane , dendrimer , cycloaddition , click chemistry , computer science , azide , scaffold , chemistry , combinatorial chemistry , polymer chemistry , organic chemistry , catalysis , programming language , polymer
Platonic scaffold : Octa(azidopropyl) cube‐octameric silsesquioxane is a versatile scaffold for uniform eightfold symmetric decoration by efficient Huisgen‐type 1,3‐dipolar cycloaddition under both thermal and Cu I ‐catalyzed conditions (see scheme). Applications are demonstrated for the formation of glycoclusters, as well as an entry to dendrimer synthesis by functional azide‐to‐alkyne reversion with implicit doubling to sixteenfold attachment sites.