Premium
Rapid and Selective Catalytic Oxidation of Secondary Alcohols at Room Temperature by Using (N‐Heterocyclic Carbene)–Ni 0 Systems
Author(s) -
Berini Christophe,
Winkelmann Ole H.,
Otten Jennifer,
Vicic David A.,
Navarro Oscar
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201000220
Subject(s) - carbene , catalysis , anhydrous , chemistry , solvent , alcohol oxidation , organic chemistry , photochemistry , medicinal chemistry
The selective, anaerobic catalytic oxidation of secondary alcohols at room temperature by using an in situ (N‐heterocyclic carbene)–Ni 0 system is presented. The use of non‐anhydrous, non‐degassed 2,4‐dichlorotoluene as both the oxidant and the solvent allows for very short reaction times and very high yields. In addition, a well‐defined (N‐heterocyclic carbene)–Ni 0 complex was synthesized and applied to these oxidation reactions.