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Selective Palladium‐Catalyzed Aminocarbonylation of Aryl Halides with CO and Ammonia
Author(s) -
Wu XiaoFeng,
Neumann Helfried,
Beller Matthias
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201000090
Subject(s) - palladium , halide , catalysis , aryl , ammonia , chemistry , combinatorial chemistry , organic chemistry , alkyl
Wake up and smell the ammonia! A palladium‐catalyzed aminocarbonylation of aryl halides with CO and ammonia has been developed (see scheme). Primary amides are accessible, under mild reaction conditions, in moderate to excellent yields.