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Cover Picture: Hydrophilic Interaction Chromatography Based Enrichment of Glycopeptides by Using Click Maltose: A Matrix with High Selectivity and Glycosylation Heterogeneity Coverage (Chem. Eur. J. 46/2009)
Author(s) -
Yu Long,
Li Xiuling,
Guo Zhimou,
Zhang Xiuli,
Liang Xinmiao
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200990181
Subject(s) - glycopeptide , click chemistry , chemistry , glycosylation , maltose , glycoproteomics , hydrogen bond , chromatography , hydrophilic interaction chromatography , matrix (chemical analysis) , combinatorial chemistry , high performance liquid chromatography , biochemistry , organic chemistry , molecule , sucrose , antibiotics
A new matrix… developed for glycoproteomic studies is described by X. Liang et al. in their Full Paper on page 12618 ff. Click maltose exhibits superior performance in glycopeptide enrichment owing to its flexible saccharide chain structure, which can effectively capture glycopeptides through enhanced hydrogen‐bonding interactions.