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Cover Picture: Cyclometalated Platinum(II) Complexes as Highly Sensitive Luminescent Switch‐On Probes for Practical Application in Protein Staining and Cell Imaging (Chem. Eur. J. 15/2009)
Author(s) -
Wu Peng,
Wong Ella LaiMing,
Ma DikLung,
Tong Glenna SoMing,
Ng KwanMing,
Che ChiMing
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200990048
Subject(s) - staining , sodium dodecyl sulfate , photoluminescence , platinum , covalent bond , luminescence , gel electrophoresis , chemistry , polyacrylamide gel electrophoresis , electrophoresis , biophysics , photochemistry , materials science , biochemistry , biology , organic chemistry , optoelectronics , enzyme , catalysis , genetics
Photoluminescent cyclometalated platinum(II) complexes can bind non‐covalently and non‐specifically towards various proteins and such bonding is accompanied by a dramatic increase in the intensity of photoluminescence in the visible spectral region. It can be practically applied for staining protein mixtures in 1D and 2D SDS‐PAGE, giving emissive gel images directly under UV light without any de‐staining procedures. For more information see the Communication by C.‐M. Che et al. on page 3652 ff. (SDS‐PAGE=sodium dodecyl sulfate polyarcylamide gel electrophoresis).