Premium
Residual Dipolar Couplings (RDCs) Analysis of Small Molecules Made Easy: Fast and Tuneable Alignment by Reversible Compression/Relaxation of Reusable PMMA Gels
Author(s) -
Gayathri Chakicherla,
Tsarevsky Nicolay V.,
Gil Roberto R.
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200903378
Subject(s) - relaxation (psychology) , isotropy , anisotropy , residual dipolar coupling , dipole , residual , compression (physics) , molecule , materials science , computer science , combinatorial chemistry , chemistry , physics , algorithm , organic chemistry , optics , composite material , psychology , social psychology
Tuneable RDCs : A fast and tunable method for measuring anisotropic NMR parameters using variable compression/relaxation of clean and reusable PMMA gels in CDCl 3 is introduced (see picture). No special devices are needed. The configuration and conformation of small molecules can be determined by using the RDC slopes without the need for performing a control experiment in isotropic conditions.