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Selective Ruthenium‐Catalyzed Alkylation of Indoles by Using Amines
Author(s) -
Imm Sebastian,
Bähn Sebastian,
Tillack Annegret,
Mevius Kathleen,
Neubert Lorenz,
Beller Matthias
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200903261
Subject(s) - ruthenium , catalysis , alkylation , chemistry , hydrogen , transfer hydrogenation , organic chemistry , combinatorial chemistry , metal
Lend me your hydrogen! The first transition‐metal‐catalyzed alkylations of indoles with aliphatic amines proceeding under transfer hydrogenation conditions are developed (see scheme). This reaction is based on the borrowing hydrogen methodology.