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Evidence for Drug Release from a Metalla‐Cage Delivery Vector Following Cellular Internalisation
Author(s) -
Zava Olivier,
Mattsson Johan,
Therrien Bruno,
Dyson Paul J.
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200903216
Subject(s) - cage , cationic polymerization , chemistry , trojan horse , drug delivery , fluorescence , biophysics , drug , combinatorial chemistry , nanotechnology , polymer chemistry , computer science , materials science , pharmacology , organic chemistry , computer security , biology , engineering , physics , structural engineering , quantum mechanics
A new journey in the Trojan horse odyssey : Encapsulation of a fluorescent guest in the hydrophobic cavity of a cationic metalla‐prismatic cage shows that the guest is released following cellular uptake, which illustrates the potential of this kind of water‐soluble metalla‐cage to act as drug carrier.