Trihydroxytrioxatriangulene—An Extended Fluorescein and a Ratiometric pH Sensor | Zendy

Westerlund Fredrik | Zendy; Hildebrandt Christoffer B. | Zendy; Sørensen Thomas J. | Zendy; Laursen Bo W. | Zendy

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Trihydroxytrioxatriangulene—An Extended Fluorescein and a Ratiometric pH Sensor

Author(s) -

Westerlund Fredrik,

Hildebrandt Christoffer B.,

Sørensen Thomas J.,

Laursen Bo W.

Publication year - 2010

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.200902965

Subject(s) - fluorescein , fluorescence , protonation , chemistry , computer science , combinatorial chemistry , optics , organic chemistry , physics , ion

Fluorescein ver. 2.0 : A new, highly fluorescent, pH‐sensitive trihydroxytrioxatriangulenium dye (H‐TOTA) has been synthesised and characterised. The dye is closely related to fluorescein and may be considered to be a two‐dimensional extended version. This new dye can exist in four different protonation states (see graphic) depending on the pH, and its use as a sensitive fluorescent ratiometric pH probe in a physiological buffer is demonstrated.

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