Premium
Dual Organocatalytic Ion‐Pair Assemblies: A Highly Efficient Approach for the Enantioselective Oxa‐Michael–Mannich Reaction of Salicylic Aldehydes with Cyclohexenones
Author(s) -
Xia AiBao,
Xu DanQian,
Luo ShuPing,
Jiang JunRong,
Tang Jie,
Wang YiFeng,
Xu ZhenYuan
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200902540
Subject(s) - enantioselective synthesis , michael reaction , domino , mannich reaction , organocatalysis , chemistry , combinatorial chemistry , salicylic acid , dual (grammatical number) , organic chemistry , catalysis , art , biochemistry , literature
Better in pairs : A highly efficient asymmetric reaction of salicylic aldehydes with cyclohexenones by means of a domino oxa‐Michael–Mannich pathway has been achieved by using novel dual organocatalytic ion‐pair assemblies from pyrrolidines and readily available primary amino acids (see scheme).