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Rhodium/Phosphine/Amine⋅HBr Catalyst System for Highly Selective Cross‐Cyclodimerization of Aryl‐ and Alkylalkynes: Efficient Access to Multisubstituted Naphthalene Derivatives
Author(s) -
Sakabe Koichi,
Tsurugi Hayato,
Hirano Koji,
Satoh Tetsuya,
Miura Masahiro
Publication year - 2010
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200902519
Subject(s) - rhodium , catalysis , phosphine , aryl , amine gas treating , chemistry , naphthalene , combinatorial chemistry , organic chemistry , alkyl
Trinity : The combination of rhodium/phosphine/amine⋅HBr enables the highly selective catalytic cross‐cyclodimerization of diarylacetylenes with aliphatic alkynes to afford the corresponding multiply substituted naphthalenes in good‐to‐high yields. The catalyst system also allows the use of some alkenes as the coupling partners, which provides a facile route to highly functionalized dihydronaphthalenes (see scheme).