Premium
Gold(I)‐Catalyzed Synthesis of Highly Substituted 2‐Cyclopentenones from 5‐Siloxypent‐3‐en‐1‐ynes
Author(s) -
An Sang Eun,
Jeong Jihee,
Baskar Baburaj,
Lee Joopyung,
Seo Junho,
Rhee Young Ho
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200901824
Subject(s) - yield (engineering) , catalysis , quaternary carbon , chemistry , center (category theory) , medicinal chemistry , organic chemistry , materials science , metallurgy , enantioselective synthesis , crystallography
More than a protective group! A highly efficient synthesis of 2‐cyclopentenones, possessing a quaternary carbon center, from 5‐siloxypent‐3‐en‐1‐ynes was discovered (see scheme). The reaction proceeded under very mild conditions to provide the products in high yield.