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Studies on the Tandem Reaction of 4‐Aryl‐2,3‐allenoates with Organozinc Reagents: A Facile Route to Polysubstituted Naphthols
Author(s) -
Chai Guobi,
Lu Zhan,
Fu Chunling,
Ma Shengming
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200901779
Subject(s) - tandem , reagent , aryl , combinatorial chemistry , computer science , scheme (mathematics) , chemistry , database , organic chemistry , engineering , mathematics , mathematical analysis , alkyl , aerospace engineering
Diversified polysubstituted α‐naphthols have been efficiently constructed through a tandem reaction of easily available 2,3‐allenoates and organozinc reagents in moderate to excellent yields (see scheme). Some of the products may undergo a couple of sequential coupling reactions to afford polysubstituted naphthalenes.