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Catalytic Organocopper Chemistry from Organosiloxane Reagents
Author(s) -
Herron Jessica R.,
Russo Vincenzo,
Valente Edward J.,
Ball Zachary T.
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200901438
Subject(s) - silane , reagent , catalysis , reactivity (psychology) , chemistry , stoichiometry , fluoride , ligand (biochemistry) , combinatorial chemistry , copper , computer science , organic chemistry , inorganic chemistry , medicine , biochemistry , alternative medicine , receptor , pathology
Organosilanes serve as precursors to organocopper intermediates in a copper‐catalyzed addition to vinylepoxides (see scheme). Ligand structure has a significant effect on the reactivity of the organocopper intermediate, and the catalysis proceeds without the need for a stoichiometric silane activator such as fluoride.