Single‐Domain Antibody‐Conjugated Nanoaggregate‐Embedded Beads for Targeted Detection of Pathogenic Bacteria | Zendy

Huang PingJi | Zendy; Tay LiLin | Zendy; Tanha Jamshid | Zendy; Ryan Shan | Zendy; Chau LaiKwan | Zendy

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Single‐Domain Antibody‐Conjugated Nanoaggregate‐Embedded Beads for Targeted Detection of Pathogenic Bacteria

Author(s) -

Huang PingJi,

Tay LiLin,

Tanha Jamshid,

Ryan Shan,

Chau LaiKwan

Publication year - 2009

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.200901397

Subject(s) - single domain antibody , staphylococcus aureus , pathogenic bacteria , bacteria , conjugated system , antibody , phage display , chemistry , materials science , microbiology and biotechnology , nanotechnology , biology , polymer , immunology , genetics , organic chemistry

Cells aglow : Nanoaggregate‐embedded beads (NAEBs) linked to a pathogen‐specific single‐domain antibody (sdAb) are used as an ultra‐bright surface‐enhanced Raman scattering (SERS) tag for detection of Staphylococcus aureus bacteria by SERS microscopy. The image shows a single S. aureus cell labeled with NAEBs and its corresponding NAEB–SERS spectrum.

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