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Fluorescent Diarylindoles by Palladium‐Catalyzed Direct and Decarboxylative Arylations of Carboxyindoles
Author(s) -
Miyasaka Mitsuru,
Fukushima Azusa,
Satoh Tetsuya,
Hirano Koji,
Miura Masahiro
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200900098
Subject(s) - palladium , fluorescence , catalysis , chemistry , combinatorial chemistry , organic chemistry , physics , optics
Simple and brilliant : 1‐Substituted 1 H ‐indole‐2‐carboxylic acids efficiently undergo successive diarylation accompanied by CH bond cleavage and decarboxylation upon treatment with aryl bromides in the presence of a palladium catalyst system to afford fluorescent 2,3‐diarylindoles. This facile synthetic method provides a highly efficient blue emitter with a quantum yield of 0.97 in the solid state (see scheme).