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Cover Picture: PAMAM Structure‐Based Multifunctional Fluorescent Conjugates for Improved Fluorescent Labelling of Biomacromolecules (Chem. Eur. J. 27/2008)
Author(s) -
Wängler C.,
Moldenhauer G.,
Saffrich R.,
Knapp E.M.,
Beijer B.,
Schnölzer M.,
Wängler B.,
Eisenhut M.,
Haberkorn U.,
Mier W.
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200890107
Subject(s) - fluorescence , chemistry , dendrimer , racemization , stereochemistry , polymer chemistry , physics , quantum mechanics
Fluorescent labeling of biomacromolecules with molecules that produce strong fluorescence allows the structures and functions of healthy as well as tumor cells to be investigated. In their Full Paper on page 8116 ff. , W. Mier et al. describe the synthesis and characterization of dye oligomers with multiple fluorescent moieties attached to polyamidoamine (PAMAM) dendrimers. These dye oligomers can then be attached to biomacromolecules, such as antibodies, and retain their fluorescent activity.