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Encapsulation and Sustained Release of Curcumin using Superparamagnetic Silica Reservoirs
Author(s) -
Chin Suk Fun,
Iyer K. Swaminathan,
Saunders Martin,
St. Pierre Tim G.,
Buckley Craig,
Paskevicius Mark,
Raston Colin L.
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200802747
Subject(s) - curcumin , superparamagnetism , nanoparticle , materials science , porosity , nanotechnology , chemical engineering , aqueous solution , matrix (chemical analysis) , magnetic nanoparticles , porous medium , chemistry , composite material , organic chemistry , magnetization , magnetic field , engineering , biochemistry , physics , quantum mechanics
For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe 3 O 4 particles surrounded by a silica matrix.