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Cyclometalated Platinum(II) Complexes as Highly Sensitive Luminescent Switch‐On Probes for Practical Application in Protein Staining and Cell Imaging
Author(s) -
Wu Peng,
Wong Ella LaiMing,
Ma DikLung,
Tong Glenna SoMing,
Ng KwanMing,
Che ChiMing
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200802707
Subject(s) - platinum , luminescence , staining , sodium dodecyl sulfate , biomolecule , chemistry , biophysics , nanotechnology , materials science , biochemistry , biology , optoelectronics , catalysis , genetics
Abstract Protein‐staining platinum : The luminescent switch‐on characteristic of the platinum(II) complex can be utilized for staining a series of proteins in sodium dodecyl sulfate‐polyarcylamide gels, to give emissive gel images directly under UV light (see figure). The detection sensitivity for BSA protein is down to 6.0 ng, revealing potential practical applications of luminescent platinum(II) complexes in the luminescent signaling of biomolecules.