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Control of the Supramolecular Excimer Formation of Thioflavin T within a Cucurbit[8]uril Host: A Fluorescence On/Off Mechanism
Author(s) -
Mohanty Jyotirmayee,
Dutta Choudhury Sharmistha,
Upadhyaya Hari P.,
Bhasikuttan Achikanath C.,
Pal Haridas
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200802686
Subject(s) - thioflavin , excimer , fluorescence , supramolecular chemistry , dissociation (chemistry) , chemistry , photochemistry , crystallography , biophysics , optics , biology , physics , crystal structure , disease , alzheimer's disease , medicine , pathology
On or off? A new excimer band at λ =570 nm was visualized during the noncovalent host–guest interaction between thioflavin T (ThT) and cucurbit[8]uril (CB8). Controlled dissociation of this assembly in the presence of Ca 2+ was demonstrated as an on/off fluorescence switch (see picture).