A General Palladium‐Catalyzed Amination of Aryl Halides with Ammonia | Zendy

Schulz Thomas | Zendy; Torborg Christian | Zendy; Enthaler Stephan | Zendy; Schäffner Benjamin | Zendy; Dumrath Andreas | Zendy; Spannenberg Anke | Zendy; Neumann Helfried | Zendy; Börner Armin | Zendy; Beller Matthias | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A General Palladium‐Catalyzed Amination of Aryl Halides with Ammonia

Author(s) -

Schulz Thomas,

Torborg Christian,

Enthaler Stephan,

Schäffner Benjamin,

Dumrath Andreas,

Spannenberg Anke,

Neumann Helfried,

Börner Armin,

Beller Matthias

Publication year - 2009

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.200802678

Subject(s) - phosphine , catalysis , palladium , halide , amination , aryl , ammonia , chemistry , ligand (biochemistry) , organic chemistry , inorganic chemistry , polymer chemistry , biochemistry , alkyl , receptor

A new robust palladium/phosphine catalyst system for the selective monoarylation of ammonia with different aryl bromides and chlorides has been developed. The active catalyst is formed in situ from [Pd(OAc) 2 ] and air‐ and moisture‐stable phosphines as easy‐to‐handle pre‐catalysts. The productivity of the catalyst system is comparable to that of competitive Pd/phosphine systems; full conversion is achieved with most substrates with 1–2 mol % of Pd source and a fourfold excess of ligand (L).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research