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Guanosine Hydrogen‐Bonded Scaffolds: A New Way to Control the Bottom‐Up Realisation of Well‐Defined Nanoarchitectures
Author(s) -
Lena Stefano,
Masiero Stefano,
Pieraccini Silvia,
Spada Gian Piero
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200802506
Subject(s) - supramolecular chemistry , guanosine , guanine , moiety , hydrogen bond , covalent bond , nanotechnology , molecule , chemistry , scaffold , combinatorial chemistry , non covalent interactions , materials science , stereochemistry , computer science , organic chemistry , biochemistry , nucleotide , database , gene
Over the last two decades, guanosine‐related molecules have been of interest in different areas, ranging from structural biology to medicinal chemistry, supramolecular chemistry and nanotechnology. The guanine base is a multiple hydrogen‐bonding unit, capable also of binding to cations, and fits very well with contemporary studies in supramolecular chemistry, self‐assembly and non‐covalent synthesis. This Concepts article, after reviewing on the diversification of self‐organised assemblies from guanosine‐based low‐molecular‐weight molecules, will mainly focus on the use of guanine moiety as a potential scaffold for designing functional materials of tailored physical properties.