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Cu II –Hydrotalcite as an Efficient Heterogeneous Catalyst for Huisgen [3+2] Cycloaddition
Author(s) -
Namitharan Kayambu,
Kumarraja Mayilvasagam,
Pitchumani Kasi
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200802384
Subject(s) - cycloaddition , hydrotalcite , catalysis , regioselectivity , reactivity (psychology) , chemistry , click chemistry , reusability , combinatorial chemistry , organic chemistry , computer science , medicine , alternative medicine , software , pathology , programming language
Top Cat! Cu II –hydrotalcite (HT) is used as a catalyst for the regioselective synthesis of 1,4‐disubstituted 1,2,3‐triazoles by [3+2] cycloaddition of various azides and alkynes. The catalyst enjoys advantages such as faster reactivity, good stability, reusability, high catalytic activity without any additives at room temperature, and does not require a nitrogen atmosphere for this “click‐chemistry” transformation.