Total Synthesis of Phosphatidylinositol Dimannoside: A Cell‐Envelope Component of  Mycobacterium tuberculosis | Zendy

Patil Pratap S. | Zendy; Hung ShangCheng | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Total Synthesis of Phosphatidylinositol Dimannoside: A Cell‐Envelope Component of Mycobacterium tuberculosis

Author(s) -

Patil Pratap S.,

Hung ShangCheng

Publication year - 2009

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.200802189

Subject(s) - phosphatidylinositol , mycobacterium tuberculosis , component (thermodynamics) , envelope (radar) , tuberculosis , cell envelope , microbiology and biotechnology , biology , medicine , physics , genetics , computer science , pathology , signal transduction , telecommunications , gene , escherichia coli , thermodynamics , radar

A concise synthesis of phosphatidylinositol dimannoside (PIM 2 ) from commercially available myo ‐inositol 1,3,5‐orthoformate via a highly regioselective and stereoselective 6‐ O ‐mannosylation of the myo ‐inositol‐derived meso ‐4,6‐diol as a key step was carried out in 9 steps (see scheme) and in 13 % overall yield.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research