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A New Gold‐Catalyzed Domino Cyclization and Oxidative Coupling Reaction
Author(s) -
Wegner Hermann A.,
Ahles Sebastian,
Neuburger Markus
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200801848
Subject(s) - domino , alkyne , catalysis , combinatorial chemistry , oxidative phosphorylation , chemistry , oxidative coupling of methane , natural product , coupling (piping) , organic chemistry , materials science , biochemistry , metallurgy
Gold double feature : A new gold‐catalyzed domino cyclization/oxidative coupling reaction is presented, wherein the same catalyst promotes the cyclization of the alkyne group in arylpropionic esters onto the arene, as well as the oxidative homocoupling of the resulting bicyclic coumarin product to the dicoumarin, an interesting scaffold, for example, in many natural products.