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Investigation of sp 2 –sp Coupling for Electron‐Enriched Aryl Dihalides under Oxygen‐Free Sonogashira Coupling Reaction Conditions Using a Two‐Chamber Reaction System
Author(s) -
Chen XueYi,
Barnes Charles,
Dias Jerry R.,
Sandreczki T. C.
Publication year - 2009
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200801541
Subject(s) - sonogashira coupling , triethylamine , aryl , yield (engineering) , coupling reaction , photochemistry , chemistry , materials science , palladium , catalysis , organic chemistry , alkyl , metallurgy
Triethylamine hydroiodide crystals were formed during Sonogashira reactions; after complete reaction the solution retains a characteristic light color (see picture). Very sluggish Sonogashira reactions of electron‐enriched aryl diiodides have been carried out in high yield in an oxygen‐free, two‐chamber reaction system. The formation of triethylamine hydroiodide crystals was monitored to determine the completion of reaction.