Premium
Cephalosol: An Antimicrobial Metabolite with an Unprecedented Skeleton from Endophytic Cephalosporium acremonium IFB‐E007
Author(s) -
Zhang Hua Wei,
Huang Wu Yang,
Chen Jing Rong,
Yan Wei Zhong,
Xie Dai Qian,
Tan Ren Xiang
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200801000
Subject(s) - acremonium , endophyte , secondary metabolite , antimicrobial , metabolite , apocynaceae , biology , botany , plant use of endophytic fungi in defense , chemistry , microbiology and biotechnology , biochemistry , gene
Cephalosol ( 1 ), a potent antimicrobial secondary metabolite with a new carbon skeleton, was characterized from the culture of Cephalosporium acremonium IFB‐E007 that used to reside as an endophyte in Trachelospermum jasminoides (Apocynaceae). Its structure and absolute configuration were unambiguously determined by spectroscopic and computational approaches.