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Organometallic–Polypeptide Block Copolymers: Synthesis and Self‐Assembly of Poly(ferrocenyldimethylsilane)‐b‐Poly( ε ‐benzyloxycarbonyl‐ L ‐Lysine)
Author(s) -
Wang Yishan,
Zou Shan,
Kim Kyoung Taek,
Manners Ian,
Winnik Mitchell A.
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200800762
Subject(s) - copolymer , micelle , lamellar structure , polymer chemistry , lysine , solvent , polymerization , nucleation , self assembly , chemistry , crystallography , materials science , amino acid , aqueous solution , polymer , organic chemistry , biochemistry
A new type of metallopolymer‐polypeptide block copolymer poly(ferrocenyldimethylsilane)‐ b ‐poly ( ε ‐benzyloxycarbonyl‐ l‐ lysine) was synthesized by ring‐opening polymerization of ε ‐benzyloxycarbonyl‐ l‐ lysine N‐carboxyanhydride initiated by using a primary amino‐terminated poly(ferrocenyldimethylsilane). Studies on the self‐organization behavior of this polypeptide block copolymer in both the bulk state and in solution were performed. In the bulk state, a cylindrical‐in‐lamellar structure was observed in a compositionally asymmetric sample. Rod‐like micelles with a polyferrocenylsilane core formed in a polypeptide‐selective solvent alone or in the presence of a common solvent. Significantly, an additional small quantity of the common solvent assisted the formation of longer micelles and micelles with better shape‐regularity. This is attributed to a decrease in the number of nucleation events and PFS core reorganization effects.