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TTF‐Modified DNA
Author(s) -
Bouquin Nicolas,
Malinovskii Vladimir L.,
Guégano Xavier,
Liu ShiXia,
Decurtins Silvio,
Häner Robert
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200800505
Subject(s) - perylene , oligonucleotide , pyrene , tetrathiafulvalene , quenching (fluorescence) , diimide , exciton , fluorescence , chemistry , dna , materials science , physics , molecule , optics , biochemistry , condensed matter physics , organic chemistry
Highly organized : Tetrathiafulvalene(TTF)‐modified oligonucleotides form stable double strands (see graphic). Exciton coupling reveals a high degree of structural organization in the modified region of a hetero‐duplex formed by TTF and perylene diimide‐containing strands. Fluorescence quenching in TTF/pyrene‐modified hetero‐hybrids is demonstrated. The results presented are important for the development of redox‐active, oligonucleotide‐based diagnostics or optical sensors.