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Copper‐ or Iron‐Catalyzed Arylation of Phenols from respectively Aryl Chlorides and Aryl Iodides
Author(s) -
Xia Ning,
Taillefer Marc
Publication year - 2008
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.200800436
Subject(s) - aryl , phenols , chemistry , catalysis , copper , ligand (biochemistry) , organic chemistry , principal (computer security) , combinatorial chemistry , medicinal chemistry , computer science , biochemistry , alkyl , receptor , operating system
The first general entry into copper‐catalyzed arylation of phenols from aryl chlorides is the principal outcome of the study presented in this article. The use of the 2,2,6,6‐tetramethyl‐3,5‐heptanedione ( 1 ) as ligand is the key to the success of this reaction. An additional finding of this study, touched upon only briefly here, is the 1 /Fe‐catalyzed arylation of phenols from aryl iodides (R=a donating or an electron‐withdrawing group).