Tandem Intramolecular Hydroalkoxylation–Hydroarylation Reactions: Synthesis of Enantiopure Benzofused Cyclic Ethers from the Chiral Pool | Zendy

Barluenga José | Zendy; Fernández Amadeo | Zendy; Satrústegui Amaya | Zendy; Diéguez Alejandro | Zendy; Rodríguez Félix | Zendy; Fañanás Francisco J. | Zendy

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Tandem Intramolecular Hydroalkoxylation–Hydroarylation Reactions: Synthesis of Enantiopure Benzofused Cyclic Ethers from the Chiral Pool

Author(s) -

Barluenga José,

Fernández Amadeo,

Satrústegui Amaya,

Diéguez Alejandro,

Rodríguez Félix,

Fañanás Francisco J.

Publication year - 2008

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.200800312

Subject(s) - enantiopure drug , tandem , intramolecular force , chemistry , catalysis , aryl , combinatorial chemistry , stereochemistry , medicinal chemistry , enantioselective synthesis , organic chemistry , materials science , alkyl , composite material

Progressive cycling! Highly functionalized benzofused oxabicyclo[3.3.1]nonanes are easily obtained from simple aryl‐substituted alquinol derivatives by a catalytic tandem sequence involving an hydroalkoxylation reaction followed by a hydroarylation process, shown here.

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